Background and objectives: Increasing evidence suggested the roles of endothelial cells and ATP-sensitive potassium channels (KATP channels) in cardioprotection during cardiac surgery.  However, there are limited data demonstrating the effects of endothelial KATP activators on endothelial cell viability and NO production in the absence and the presence of hyperkalemic cardioplegia (CPG) against ischemia-reperfusion injury (IRI). The aims of this study were to investigate the early and late ef...

This research employed a research and development methodology to: 1) develop  a blended learning model based on project-based learning to enhance innovative thinking skills for vocational students, 2) study the outcomes of implementing the blended learning model, and 3) validate the developed blended learning model. The sample group consisted of 25 students from the Digital Business Technology program, Diploma level 1.1, at Phitsanulok Vocational College, during the first semester of the 2...

The physical health of adolescents in Bhutan is of national importance, with rising non-communicable diseases (NCDs) like obesity and cardiovascular conditions necessitating early intervention. However, the current physical education (PE) curriculum has shown limited effectiveness in improving health-related fitness (HRF) due to insufficient activity frequency and targeted interventions. This study addresses this gap by evaluating a structured Physical Activity Program (PAP) grounded in the F...

The purpose of this research is to develop an entrepreneurial leadership development model for students under the office of the Vocational Education Commission. The research was conducted in four steps, as follows: 1) a study of elements and guidelines for the development of entrepreneurial leadership for students under the office of the Vocational Education Commission from the analysis of relevant research papers Interviews with school administrators and entrepreneurs of 4 locations with goo...

Our case study, a distribution network, had a high rate of lost sales due to a mismatch between the inventory level and the demand and the variability of peddling demand. Three main inventory replenishment policies were required: Regular and urgent orders to the factory and lateral transshipment orders between distribution centers. Moreover, two types of demands are considered: pre-order and peddling demands. A spreadsheet model simulated this system to compare a set of proposed inventory rep...

Sugarcane harvesters are agricultural machines that has an important role in the sugarcane industry in Thailand. They improve the harvesting process by reducing labor dependency and reducing the air pollution (PM2.5) caused by sugarcane burning in Thailand. This research aimed to study the performance of sugarcane harvesters being used in Lower North region, physical properties and shear forces of sugarcane billets and the effect of base cutters to provide the data for developing the sugarcan...

Curcumin is a multitherapeutic agent with great therapeutic potential in central nervous system (CNS) diseases. However, its hydrophobicity and low bioavailability hinder its application. To circumvent these drawbacks, we developed polymer-based and lipid-based curcumin nano-formulations. This study aimed to compare the physicochemical properties, in vitro release studies, permeation studies in Caco-2 cells and antidepressant activity of polymer-based and lipid-based of curcumin nano-formu...